Contents. List of Contributors. Preface (G.H. Heppner). Cellular Genetic Alterations: Models of Breast and Colon Cancer (S.R. Wolman and D.W. Visscher). Altered Expression of Transforming Growth Factor-a and Transforming Growth Factor-Ã Autocrine Loops in Cancer Cells (M.G. Brattain, K.M. Mulder, S.P. Wu, G. Howell, L. Sun, J.K.V. Willson, and B.L. Ziober). Altered Signal Transduction in Carcinogenesis (C.A. O'Brian, N.E. Ward, and C.G. Ioannides). The Significance of the Extracellular Matrix in Mammary Epithelial Carcinogenesis (C.D. Roskelley, O.W. Petersen, and M.J. Bissell). Epithelial-Stromal Cell Interactions and Breast Cancer (S.Z. Haslam, L.J. Counterman, and K.A. Nummy). The Tissue Matrix and the Regulation of Gene Expression in Cancer Cells (K.J. Pienta, B.C. Murphy, R.H. Getzenberg, and D.S. Coffey). Tumor Cell Interactions in Cancer Growth and Expression of the Malignant Phenotype (F.R. Miller and B.E. Miller). Effects of Class 1 MHC Gene Products on the Immunobiological Properties of BL6 Melanoma Cells (M. Kim and E. Gorelik). The Role of Angiogenesis in Tumor Progression and Metastasis (J.W. Rak, E.J. Hegmann, and R.S. Kerbel). Index.