Biological Identification book cover

Biological Identification

DNA Amplification and Sequencing, Optical Sensing, Lab-On-Chip and Portable Systems

Biological Identification provides a detailed review of, and potential future developments in, the technologies available to counter the threats to life and health posed by natural pathogens, toxins, and bioterrorism agents. Biological identification systems must be fast, accurate, reliable, and easy to use. It is also important to employ the most suitable technology in dealing with any particular threat. This book covers the fundamentals of these vital systems and lays out possible advances in the technology.

Part one covers the essentials of DNA and RNA sequencing for the identification of pathogens, including next generation sequencing (NGS), polymerase chain reaction (PCR) methods, isothermal amplification, and bead array technologies. Part two addresses a variety of approaches to making identification systems portable, tackling the special requirements of smaller, mobile systems in fluid movement, power usage, and sample preparation. Part three focuses on a range of optical methods and their advantages. Finally, part four describes a unique approach to sample preparation and a promising approach to identification using mass spectroscopy.

Biological Identification is a useful resource for academics and engineers involved in the microelectronics and sensors industry, and for companies, medical organizations and military bodies looking for biodetection solutions.


Biological Identification is a useful resource for academics and engineers involved in the microelectronics and sensors industry, and for companies, medical organisations and military bodies looking for biodetection solutions.

Hardbound, 470 Pages

Published: May 2014

Imprint: Woodhead Publishing

ISBN: 978-0-85709-501-5


  • A veritable encyclopedia of some of the latest advances in technology and procedures for biological detection and analysis., Dr. John Vitko, former Director of the Chemical and Biological Defense Division of the Science and Technology Directorate of the Department of Homeland Security


  • Part 1 Technology for DNA and RNA analysis of pathogens

    Nucleic acid sequencing for characterizing infectious and/or novel agents in complex samples
    C. Detter, Los Alamos National laboratory, USA

    Multiplexed, lateral flow, polymerase chain reaction (PCR) techniques for biological identification
    W. M. Nelson, G. W. Long and L. M. Cockrell, Tetracore, USA

    Isothermal amplification of specific sequences
    Y. Tong, New England Biolabs, USA

    Bead array technologies for genetic disease screening and microbial detection
    S.A. Dunbar and S.V. Angeloni, Luminex Corporation, USA

    Part 2 Lab-on-chip and portable systems for biodetection and analysis

    Electrochemical detection for biological identification
    P. Skládal, Masaryk University, Czech Republic

    Conductometric biosensors
    S. Dzyadevych, National Academy of Sciences of Ukraine, Ukraine and N. Jaffrezic-Renault, University of Lyon, France

    Bio-chem-FETs: field effect transistors for biological sensing
    N. Chaniotakis and M. Fouskaki, University of Crete, Greece

    Microfluidic devices for rapid identification and characterization of pathogens
    H. Becker, Microfluidic ChipShop GmbH, Germany

    Part 3 Optical systems for biological identification

    Optical Biodetection using Receptors and Enzymes (Porphyrin-Incorporated)
    H. J. Harmon and A. Oliver, Oklahoma State University, USA

    Overview of THz spectral characterization for biological identification
    T. Globus, B. Gelmont and I. Sizov, University of Virginia, USA

    Raman spectroscopy for biological identification
    T.J. Ronningen, J.M. Schuetter, J.L. Wightman, A. Murdock and A.P. Bartko, Battelle Memorial Institute, USA

    LIDAR (light detection and ranging) for biodetection
    H.S. Lee, C. R. Prasad, and R. M. Serino, Science & Engineering Services, Inc. (SESI), USA

    Part 4 Sample preparation and mass spectrometry-based biological analysis

    Electrophoretic approaches to sample collection and preparation for nucleic acids analysis.
    C. Bradburne, Johns Hopkins University, USA

    Mass spectrometry-based proteomics techniques for biological identification
    R.E. Jabbour and A. P. Snyder, US Army Edgewood Chemical Biological Center, USA


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