Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease

Prevention and Therapy

Edited by

  • Ronald Watson, Professor of Health Promotion Sciences, Mel and Enid Zuckerman Arizona College of Public Health and School of Medicine, Tucson, AZ, USA
  • Victor Preedy, Department of Dietetics, King's College London, UK

Nutritional supplement research concerning brain health and neurological disease is becoming an important focus. While nutritional supplements are very popular for general health and well being, the effectiveness of common supplements and their impact on general brain health and for the treatment or prevention of neurological disease is not clearly understood. This comprehensive introduction to bioactive nutraceuticals for brain and neurological provides a foundation review for research neuroscientists, clinical neurologists, pharmacology researchers and nutrition scientists on what we know now about these supplements and the brain and where focused research is still necessary.
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Neuroscience\Neurology Research, Nutrition Research


Book information

  • Published: September 2014
  • ISBN: 978-0-12-411462-3


"...this book is helpful as a review of the current body of literature on foods and supplements that can aid in combating neurological diseases.  Score: 80 - 3 Stars"--Doody's, Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease

Table of Contents

Section 1: Role of Complementary and alternative supplements: Overview of mechanisms of action and neurological targets
1. Anti-inflammatory properties of botanical extracts contribute to their protective effects in brain edema in cerebral ischemia
  Kiran S. Panickar
2. Blueberry polyhphenols and neuroprotection
  Marilù Giacalone, Filippo Di Sacco, Ippolito Traupe, Nicola Pagnucci, Francesco Forfori and Francesco Giunta
3. Neuropharmacology effects of saffron (Crocus sativus) and its active constituents
  Marjan Nassiri-Asl and Hossein Hosseinzadeh
4. Lutein, brain and neurological functions
  Vijaya Juturu
5. Bioactive nutrients for Brain health: an overview
  Vijaya Juturu
6. The use of Paullinia cupana  (Guarana) to treat fatigue and other symptoms of cancer and cancer treatment
  Adriana del Giglio and Auro del Giglio
7. Polyphenols, Nerve Growth factor, Brain-derived Neurotrophic Factor and the Brain
  Valentina Carito, Mauro Ceccanti, George Chaldakov, Luigi Tarani, Sara De Nicolò, Stefania Ciafrè, Paola Tirassa and Marco Fiore
8. The anti-aggregative, anti-amyloid properties of bioactive polyphenols in the treatment of Alzheimer ’s disease
  Sukanya Das and Scott D. Smid
9. Rhinacanthus nasutus extract as a neuroprotectant
  James M. Brimson and Tewin Tencomnao

Section 2: Role of diets, complementary, and alternative supplements in prevention and treatment of neurodegenerative diseases
10. Nutraceuticals, dietary supplements and functional foods as alternatives to the relief of neuropathic pain
  Gislaine Francieli da Silva, Lilian Wunsch Rocha and Nara Lins Meira Quintão
11. The Therapeutic Activities of Selected Scrophulariaceae and Buddlejaceae Species As Well As Their Secondary Metabolites Against Neurodegenerative Diseases                    
  I. Irem Tatli, Cigdem Kahraman and Zeliha Sükran Akdemir
12. Ginkgo biloba Extracts in Neurological Disorders Therapy: Clinical Trials
  I. Irem Tatli
13. The Ketogenic Diet for the Adjuvant Treatment of Malignant Brain Tumors                        
  Eric C. Woolf and Adrienne C. Scheck
14. Reduction is the new young! The effect of polyphenols on brain ageing and diseases
  Lakshana Sreenivasan and Ronald R. Watson
15. Natural sleep aids and polyphenols as treatments for insomnia
  Suengmok Cho and Makoto Shimizu
16. The effects of trace elements deficiencies on neurological disease and treatment with trace elements support
  Aysegül Bayir
17. Nutritional supplementations in Ehlers-Danlos syndromes
  Marco Castori, Michela Bruschini and Carlo Blundo

Section 3: Mood and cognition by nutriceutical interventions
18. Ayurvedic approach to food and dietary supplements in brain and neurological health
  Hari Sharma and H. M Chandola
19. The effect of acai (Euterpe spp.) fruit pulp on brain health and performance
  Alexander G. Schauss
20. Chili pepper compounds in the management of neuropathic pain
  Marilù Giacalone, Francesco Forfori and Francesco Giunta
21. Curcumin and neurological/brain disorders
  Federico Franceschi, Stefano Togni and Giovanni Appendino

Section 4: Drug and foods and nutriceutical interactions during treatment of neurodegenerative diseases: Toxicities
22. The effects of taurine exposure effects on the brain and neurological disorders  
  Sanya Roysommuti and James Michael Wyss
23. Adverse neurologic effects caused by the ingestion of plants, seeds and fruits         
  Francisco Javier Carod Artal
24. Molecular mechanisms of geniposide and genipin against Alzheimer’s disease
  Jianhui Liu, Fei Yin, Lixia Guo, Junzeng Zhang and Jeffrey Zidichouski
25. Flavones and flavonols in brain and disease: facts and pitfalls
  Florencia Arredondo, Carolina Echeverry, Fernanda Blasina, Lucía Vaamonde, Marcela Díaz, Marcela Martínez, Juan Andres Abin-Carriquiry and Federico Dajas
26. Mercury and neurodegeneration 
  Michael Aschner
27. Ameliorative Effects of Nutraceuticals in Neurological Disorders
  Neelima B. Chauhan and Jogender Mehla
28. Roles of Caffeine in Neurodegenerative Diseases: Possible Genetic and Cellular Signaling Mechanisms
  Khanh v.q. LÆ°Æ¡ng and Lan Thi Hoàng Nguyễn
29. Dietary supplements as cognitive enhancers: role of flavonoid-rich foods and their relevance in age-related neurodegeneration
  Krishna Gokul and M. Muralidhara

Section 5: Mechanisms of action of nutriceuticals and dietary supplements in neurological disease therapy: Autoimmunity and antioxidant actions
30. Meats, fats and fruit consumption and autoimmune neurological and brain disease
  Ronald R. Watson and Gurman Dhaliwal
31. Ginsenosides as food supplements and their potential role in immunological and neurodegenerative disorders
  Salman Kahn, Alev -. Tosun and Yeong Shik Kim
32. Antioxidant actions of spices and their phytochemicals on age-related Diseases
  Alev -. Tosun and Salman Kahn
33. Analgesic and anti-inflammatory effects of Crocus sativus L., (saffron)
  Bahareh Amin and Hossein Hosseinzadeh
34. Electrophilic derivatives of omega-3 fatty acids for the cure and prevention of neurodegenerative disorders
  Chiara Cipollina and Francisco J. Schopfer
35. Antioxidants in the prevention and treatment of multiple sclerosis: an overview
  C. Zuliani and Luciana Baroni
36. High Caloric Diets in Amyotrophic Lateral Sclerosis
  S. T. Ngo, F. J. Steyn, P. A. McCombe and Karin Borges

Section 6:  Hypertension and Stroke
37. Bioactive Nutriceuticals and Stroke: Activation of Endogenous Antioxidant Pathways and Molecular Mechanisms Underlying Neurovascular Protection
  Alessio Alfieri and Giovanni E. Mann
38. Oral feeding in patients with intracerebral hemorrhage: Risk versus benefits
  Hideaki Takahata
39. Neuroprotection by dietary isoflavones: Role in cerebral ischemia
  Derek A. Schreihofer
40. Vitamin K antagonists (VKA), i.e. coumarins, drugs used in prevention and treatment of cardioembolism, deep vein thrombosis and pulmonary embolism
  Francesco Marongiu and Doris Barcellona
41. Prevention of ischemia-induced neuronal apoptosis by vitamin E in stroke-prone spontaneously hypertensive rats- cellular mechanisms of antioxidant
  Kazuo Yamagata and Motoki Tagami
42. Diet, stroke, and traumatic brain injury 
  Joseph L. Cheatwood, R. W. Clough and W. J. Banz

Section 7: Seizures, epilepsy, Parkinson disease
43. A plant-food diet in the risk and management of Parkinson's Disease
  Luciana Baroni and C. Zuliani
44. Nutraceuticals and other natural products in Parkinson's disease therapy:  focus on clinical applications
  R.B. Mythri, A.K. Joshi and M.M. Srinivas Bharath
45. Ketogenic diet treatment in adults with refractory epilepsy
  Ivana Tyrlikova and Pavel Klein
46. Ketogenic diets for the treatment of epilepsy
  Ricka D. Messer and Eric H. Kossoff
47. Nutritional/metabolic therapies in animal models of ALS, Alzheimer's disease and seizures
  Csilla Ari, Raffaele Pilla and Dominic D'Agostino
48. Metabolic dysfunctions in epilepsy and novel metabolic treatment approaches                             
  Kah Ni Tan, Tanya S McDonald and Karin Borges
49. Vitamin D for the prevention of Alzheimer's disease
  Elizabeth Pogge
50. Is multiple sclerosis a sun Deprivation disease? Lessons from the past for the future path
  Tirang Reza Neyestani