Bacterial Growth and Division
Biochemistry and Regulation of Prokaryotic and Eukaryotic Division Cycles
- Stephen Cooper, University of Michigan Medical School
How does a bacterial cell grow during the division cycle? This question is answered by the codeveloper of the Cooper-Helmstetter model of DNA replication. In a unique analysis of the bacterial division cycle, Cooper considers the major cell categories (cytoplasm, DNA, and cell surface) and presents a lucid description of bacterial growth during the division cycle.The concepts of bacterial physiology from Ole MaalÃ¸e's Copenhagen school are presented throughout the book and are applied to such topics as the origin of variability, the pattern of DNA segregation, and the principles underlying growth transitions.The results of research on E. coli are used to explain the division cycles of Caulobacter, Bacilli, Streptococci, and eukaryotes. Insightful reanalysis highlights significant similarities between these cells and E.coli.With over 25 years of experience in the study of the bacterial division cycle, Cooper has synthesized his ideas and research into an exciting presentation. He manages to write a comprehensive volume that will be of great interest to microbiologists, cell physiologists, cell and molecular biologists, researchers in cell-cycle studies, and mathematicians and engineering scientists interested in modeling cell growth.
Bacteriologists, microbiologists, cell biologists and physiologists, molecular biologists, and geneticists; students in advanced bacterial cell physiology courses