Avian Immunology

Edited by

  • Karel Schat, Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA
  • Bernd Kaspers, Department of Veterinary Sciences, Faculty of Veterinary Medicine, University of Munich, Germany
  • Pete Kaiser, The Roslin Institute & R(D)SVS, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK

The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success.

The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies.

The world-wide importance of poultry protein for the human diet, as well  as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology.

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Immunologists, cell biologists, pathologists, poultry scientists, vaccinologists and veterinarians. Also zoologists, ecologists, ornithologists and evolutionary biologists interested in using immunological parameters as selection traits for studies on survival and evolution


Book information

  • Published: July 2013
  • ISBN: 978-0-12-396965-1


“This book would serve as reference that all can resort to for old and new information. This field lacks such a resource and I personally have used the first version extensively whether as refresher or to acquire new knowledge. Much of the classical discoveries in this area are not readily available to the public and this book will afford access to such information. The appendices are especially helpful as many scientists are not aware of the resources available.”--Dr. Rami A. Dalloul, Associate Professor, Dept. of Animal & Poultry Sciences, Virginia Tech, USA

Table of Contents

1. The importance of the avian immune system and its unique features. 2.Structure of the avian lymphoid system. 3. Development of the avian immune system. 4.B cells, the bursa of Fabricius and the generation of antibody repertoires. 5.Avian T cells: antigen recognition and lineage. 6. Structure and evolution of avian immunoglobulins.  7.Avian innate immune responses. 8. The avian MHC. 9. Avian antigen presenting cells. 10. Avian cytokines and chemokines. 11. Immunogenetics and mapping immunological functions. 12. The avian mucosal immune system. 13. The avian enteric immune system in health and disease. 14. The avian respiratory immune system. 15. The avian reproductive immune system. 16. Avian immunosuppressive diseases and immune evasion.17. Factors modulating the avian immune system
Autoimmune diseases of poultry. 18. Tumours of the avian immune system.  19. Practical aspects of poultry vaccination
Comparative immunology of agricultural birds. 20. Ecoimmunology. Appendix 1. Genetic stocks for immunological research. Appendix 2. Resources available for studying avian immunology.