Avery's Diseases of the Newborn

Thoroughly revised and updated, the New Edition of this definitive text explains how to care for neonates using the very latest methods. It maintains a clinical focus while providing state-of-the-art diagnosis and treatment techniques. Written by more than 55 specialists who are actively involved in the care of sick newborns, it serves as an authoritative reference for practitioners, a valuable preparation tool for neonatal board exams, and a useful resource for the entire neonatal care team.

Neonatologists, Pediatricians, Neonatal Nurses


Published: August 2004

Imprint: Saunders

ISBN: 978-0-7216-9347-7


  • I. Introduction

    - Perinatal-Neonatal Epidemiology
    - Evaluation of Therapeutic Recommendations, Database Management, and Information Retrieval
    - Ethical Decisions in the Neonatal-Perinatal Period

    II. Fetal Development

    - Placental Function and Diseases: The Placenta, Fetal Membranes, and Umbilical Cord
    - Abnormalities of Fetal Growth
    - Hormones and Development
    - Multiple Birth
    - Nonimmune Hydrops

    III. Maternal Health Affecting Neonatal Outcome

    - Endocrine Disorders in Pregnancy
    - Maternal Medical Disorders of Fetal Significance Seizure Disorders, Isoimmunization, Cancer and Mental Disorders
    - Hypertensive Complications of Pregnancy
    - Perinatal Substance Abuse

    IV. Issues in Labor and Delivery

    - Antepartum Fetal Assessment
    - Prematurity: Causes and Prevention
    - Complicated Deliveries: Overview
    - Maternal and Fetal Anesthesia and Analgesia

    V. Genetics

    - Human Genome and Relevance to Prenatal and Neonatal Screening
    - Prenatal Genetic Diagnosis
    - Evaluation of the Dysmorphic Infant
    - Genetic Disorders Presenting in Newborn

    VI. Congenital Metabolic Problems

    - Overview of Clinical Evaluation of Metabolic Disease (Case Studies)
    - Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism (Case Studies)
    - Lysosomal Storage, Peroxisomal, and Glycolosation Disorders and Smith-Lemli-Opitz Syndrome Presenting in the Neonate (Case Studies)
    - Connective Tissue Disorders and Skeletal Dysplasias (Case Studies)

    VII. Evaluation and Care of the Normal Newborn

    - Initial Evaluation: History and Physical Examination of the Newborn
    - Routine Newborn Care
    - Newborn Screening

    VIII. Care of the High-Risk Infant

    - Resuscitation in the Delivery Room
    - Temperature Regulation of the Premature Infant
    - Acid-Base, Fluid, and Electrolyte Management
    - Cardiovascular Compromise in the Newborn Infant
    - Care of the Extremely Low Birth Weight Infant
    - Pharmacologic Principles and Practicalities
    - Neonatal Pain in the 21st Century

    IX. Immunology and Infections

    - Immunology of the Fetus and Newborn
    - Fetal-Newborn HIV Infection
    - Viral Infections of the Fetus and Newborn
    - Toxoplasmosis, Syphilis, Malaria, and Tuberculosis
    - Bacterial Infections of Mother and Newborn
    - Nosocomial Infections in the Nursery
    - Fungal Infections in the Neonatal Intensive Care Unit

    X. Respiratory System

    - Lung Development : Embryology, Growth, Maturation, Developmental Biology
    - Control of Breathing
    - Pulmonary Physiology of the Newborn
    - Principles of Respiratory Monitoring and Therapy
    - Surfactant Treatment of Respiratory Disorders
    - Respiratory Distress Syndrome and Disorders of the Transition
    - Respiratory Failure in the Term Infant
    - Bronchopulmonary Dysplasia and Chronic Lung Disease
    - Anomalies of the Airway, Mediastinum and Lung Parenchyma
    - Disorders of the Pleura, Chest Wall, and Diaphragm

    XI. Cardiovascular System

    - Nomenclature and the Segmental Approach to Congenital Heart Disease
    - Embryology and Development of the Cardiovascular System
    - Echocardiography in the NICU
    - Diagnosis and Stabilization of the Newborn with Congenital Heart Disease
    - Patent Ductus Arteriousus in the Preterm Infant
    - Common Congenital Heart Disease—Presentation, Management and Outcomes
    - Arrhythmias in the Fetus and Newborn: Diagnosis and Management
    - Management of Congenital Heart Disease in the Low Birth Weight Infant
    - Long-term Neurological Outcomes in Children with Congenital Heart Disease

    XII. Neurologic System

    - Developmental Embryology, Anatomy, and Physiology of the CNS
    - Neonatal Neuroimaging
    - Malformations and Deformations of the Developing CNS
    - CNS Injury and Neuroprotection
    - Neonatal Neuromuscular Disorders
    - Neonatal Seizures
    - Risk Assessment and Neurodevelopmental Outcomes

    XIII. Nutrition

    - Enteral Nutrition for the High-Risk Neonate
    - Parenteral Nutrition

    XIV. Gastrointestinal System

    - Developmental Anatomy and Physiology of the Gastrointestinal Tract
    - Anomalies of the Gastrointestinal Tract
    - Physiologic and Inflammatory Abnormalities of the Gastrointestinal Tract
    - Abdominal Wall Problems
    - Necrotizing Enterocolitis and Short Bowel Syndrome

    XV. Hematologic System and Disorders of Bilirubin Metabolism

    - Developmental Biology of the Hematologic System
    - Hemostatic Disorders of the Newborn
    - Erythrocyte Disorders in Infancy
    - Neonatal Leukocyte Physiology and Disorders
    - Neonatal Hyperbilirubinemia

    XVI. Renal and Genitourinary Systems

    - Renal Morphogenesis and Development of Renal Function
    - Clinical Evaluation of Renal and Urinary Tract Disease
    - Developmental Abnormalities of the Kidneys
    - Developmental Abnormalities of the Genitourinary System
    - Acute and Chronic Renal Failure
    - Glomerulonephropathies and Disorders of Tubular Function
    - Infection of the Urinary Tract and Vesicoureteral Reflux
    - Renal Vascular Disease in the Newborn

    XVII. Endocrine Disorders

    - Embryology, Developmental Biology, and Anatomy of the Endocrine System
    - Disorders of Calcium and Phosphorus Metabolism
    - Disorders of the Adrenal Gland
    - Ambiguous Genitalia in the Newborn
    - Disorders of the Thyroid Gland
    - Disorders of Carbohydrate Metabolism

    XVIII. Orthopedic Conditions

    - Common Neonatal Orthopedic Ailments

    XIX. Neoplasia

    - Tumors and Neoplasia

    XX. Dermatologic Conditions

    - Newborn Skin: Development and Basic Concepts
    - Congenital and Hereditary Disorders of the Skin
    - Infections of the Skin
    - Common Newborn Dermatoses
    - Cutaneous Congenital Defects

    XXI. The Eye

    - Disorders of the Eye


    Appendix 1: Drugs

    Appendix 2: Illustrative Forms and Normal Values: Blood, CSF, Urine


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