Avery's Diseases of the Newborn


  • Sandra Juul, MD, PhD, Professor, Department of Pediatrics, University of Washington, Seattle, Washington
  • H. William Taeusch, MD, Professor and Vice Chair of Pediatrics, University of California; Chief of Pediatrics, San Francisco General Hospital, San Francisco, CA
  • Roberta Ballard, MD, Professor of Pediatrics, Obstetrics and Gynecology, University of Pennsylvania School of Medicine; Director, Division of Neonatology, Children's Hospital of Philadelphia and Hospital of the University of Pennsylvania, Philadelphia, PA
  • Christine Gleason, MD, Academic Affiliation; W. Alan Hodson Endowed Chair in Pediatrics and Head, Division of Neonatology; Pediatrics; University of Washington; Seattle, WA; US

Thoroughly revised and updated, the New Edition of this definitive text explains how to care for neonates using the very latest methods. It maintains a clinical focus while providing state-of-the-art diagnosis and treatment techniques. Written by more than 55 specialists who are actively involved in the care of sick newborns, it serves as an authoritative reference for practitioners, a valuable preparation tool for neonatal board exams, and a useful resource for the entire neonatal care team.
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Neonatologists, Pediatricians, Neonatal Nurses


Book information

  • Published: August 2004
  • Imprint: SAUNDERS
  • ISBN: 978-0-7216-9347-7

Table of Contents

I. Introduction

- Perinatal-Neonatal Epidemiology
- Evaluation of Therapeutic Recommendations, Database Management, and Information Retrieval
- Ethical Decisions in the Neonatal-Perinatal Period

II. Fetal Development

- Placental Function and Diseases: The Placenta, Fetal Membranes, and Umbilical Cord
- Abnormalities of Fetal Growth
- Hormones and Development
- Multiple Birth
- Nonimmune Hydrops

III. Maternal Health Affecting Neonatal Outcome

- Endocrine Disorders in Pregnancy
- Maternal Medical Disorders of Fetal Significance Seizure Disorders, Isoimmunization, Cancer and Mental Disorders
- Hypertensive Complications of Pregnancy
- Perinatal Substance Abuse

IV. Issues in Labor and Delivery

- Antepartum Fetal Assessment
- Prematurity: Causes and Prevention
- Complicated Deliveries: Overview
- Maternal and Fetal Anesthesia and Analgesia

V. Genetics

- Human Genome and Relevance to Prenatal and Neonatal Screening
- Prenatal Genetic Diagnosis
- Evaluation of the Dysmorphic Infant
- Genetic Disorders Presenting in Newborn

VI. Congenital Metabolic Problems

- Overview of Clinical Evaluation of Metabolic Disease (Case Studies)
- Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism (Case Studies)
- Lysosomal Storage, Peroxisomal, and Glycolosation Disorders and Smith-Lemli-Opitz Syndrome Presenting in the Neonate (Case Studies)
- Connective Tissue Disorders and Skeletal Dysplasias (Case Studies)

VII. Evaluation and Care of the Normal Newborn

- Initial Evaluation: History and Physical Examination of the Newborn
- Routine Newborn Care
- Newborn Screening

VIII. Care of the High-Risk Infant

- Resuscitation in the Delivery Room
- Temperature Regulation of the Premature Infant
- Acid-Base, Fluid, and Electrolyte Management
- Cardiovascular Compromise in the Newborn Infant
- Care of the Extremely Low Birth Weight Infant
- Pharmacologic Principles and Practicalities
- Neonatal Pain in the 21st Century

IX. Immunology and Infections

- Immunology of the Fetus and Newborn
- Fetal-Newborn HIV Infection
- Viral Infections of the Fetus and Newborn
- Toxoplasmosis, Syphilis, Malaria, and Tuberculosis
- Bacterial Infections of Mother and Newborn
- Nosocomial Infections in the Nursery
- Fungal Infections in the Neonatal Intensive Care Unit

X. Respiratory System

- Lung Development : Embryology, Growth, Maturation, Developmental Biology
- Control of Breathing
- Pulmonary Physiology of the Newborn
- Principles of Respiratory Monitoring and Therapy
- Surfactant Treatment of Respiratory Disorders
- Respiratory Distress Syndrome and Disorders of the Transition
- Respiratory Failure in the Term Infant
- Bronchopulmonary Dysplasia and Chronic Lung Disease
- Anomalies of the Airway, Mediastinum and Lung Parenchyma
- Disorders of the Pleura, Chest Wall, and Diaphragm

XI. Cardiovascular System

- Nomenclature and the Segmental Approach to Congenital Heart Disease
- Embryology and Development of the Cardiovascular System
- Echocardiography in the NICU
- Diagnosis and Stabilization of the Newborn with Congenital Heart Disease
- Patent Ductus Arteriousus in the Preterm Infant
- Common Congenital Heart Disease—Presentation, Management and Outcomes
- Arrhythmias in the Fetus and Newborn: Diagnosis and Management
- Management of Congenital Heart Disease in the Low Birth Weight Infant
- Long-term Neurological Outcomes in Children with Congenital Heart Disease

XII. Neurologic System

- Developmental Embryology, Anatomy, and Physiology of the CNS
- Neonatal Neuroimaging
- Malformations and Deformations of the Developing CNS
- CNS Injury and Neuroprotection
- Neonatal Neuromuscular Disorders
- Neonatal Seizures
- Risk Assessment and Neurodevelopmental Outcomes

XIII. Nutrition

- Enteral Nutrition for the High-Risk Neonate
- Parenteral Nutrition

XIV. Gastrointestinal System

- Developmental Anatomy and Physiology of the Gastrointestinal Tract
- Anomalies of the Gastrointestinal Tract
- Physiologic and Inflammatory Abnormalities of the Gastrointestinal Tract
- Abdominal Wall Problems
- Necrotizing Enterocolitis and Short Bowel Syndrome

XV. Hematologic System and Disorders of Bilirubin Metabolism

- Developmental Biology of the Hematologic System
- Hemostatic Disorders of the Newborn
- Erythrocyte Disorders in Infancy
- Neonatal Leukocyte Physiology and Disorders
- Neonatal Hyperbilirubinemia

XVI. Renal and Genitourinary Systems

- Renal Morphogenesis and Development of Renal Function
- Clinical Evaluation of Renal and Urinary Tract Disease
- Developmental Abnormalities of the Kidneys
- Developmental Abnormalities of the Genitourinary System
- Acute and Chronic Renal Failure
- Glomerulonephropathies and Disorders of Tubular Function
- Infection of the Urinary Tract and Vesicoureteral Reflux
- Renal Vascular Disease in the Newborn

XVII. Endocrine Disorders

- Embryology, Developmental Biology, and Anatomy of the Endocrine System
- Disorders of Calcium and Phosphorus Metabolism
- Disorders of the Adrenal Gland
- Ambiguous Genitalia in the Newborn
- Disorders of the Thyroid Gland
- Disorders of Carbohydrate Metabolism

XVIII. Orthopedic Conditions

- Common Neonatal Orthopedic Ailments

XIX. Neoplasia

- Tumors and Neoplasia

XX. Dermatologic Conditions

- Newborn Skin: Development and Basic Concepts
- Congenital and Hereditary Disorders of the Skin
- Infections of the Skin
- Common Newborn Dermatoses
- Cutaneous Congenital Defects

XXI. The Eye

- Disorders of the Eye


Appendix 1: Drugs

Appendix 2: Illustrative Forms and Normal Values: Blood, CSF, Urine