Avery's Diseases of the Newborn

Expert Consult - Online and Print

Avery’s Diseases of the Newborn, edited by Christine A. Gleason and Sherin U. Devaskar, is a practical, clinical reference for diagnosing and managing of all the important diseases affecting newborns. Thoroughly revised by a team of new editors, this edition provides new perspectives and updated coverage of genetics, nutrition, respiratory conditions, MRSA, neonatal pain, cardiovascular fetal interventions, care of the late preterm infant, and more. You can also access the fully searchable text and downloadable images online at www.expertconsult.com, making this authoritative reference ideal as a clinical resource or subspecialty review tool.


Neonatologists, pediatric residents, pediatricians, neonatal nurse practitioners

Hardbound, 1520 Pages

Published: September 2011

Imprint: Saunders

ISBN: 978-1-4377-0134-0


  • P A R T I


    Chapter 1 Neonatal and Perinatal

    Epidemiology, 1

    Chapter 2 Evaluation of Therapeutic

    Recommendations, Database

    Management, and Information

    Retrieval, 10

    Chapter 3 Ethics, Data, and Policy in

    Newborn Intensive Care, 18

    Chapter 4 Global Neonatal Health, 23

    P A R T II

    Fetal Development

    Chapter 5 Immunologic Basis of Placental

    Function and Diseases: The

    Placenta, Fetal Membranes, and

    Umbilical Cord, 37

    Chapter 6 Abnormalities of Fetal

    Growth, 51

    Chapter 7 Multiple Gestations and Assisted

    Reproductive Technology, 60

    Chapter 8 Nonimmune Hydrops, 67

    P A R T III

    Maternal Health Affecting Neonatal


    Chapter 9 Endocrine Disorders in

    Pregnancy, 75

    Chapter 10 Maternal Medical Disorders of

    Fetal Significance: Seizure Disorders,

    Isoimmunization, Cancer,

    and Mental Health Disorders, 92

    Chapter 11 Hypertensive Complications of

    Pregnancy, 105

    Chapter 12 Perinatal Substance Abuse, 111

    P A R T IV

    Labor and Delivery

    Chapter 13 Antepartum Fetal Assessment, 129

    Chapter 14 Prematurity: Causes and

    Prevention, 140

    Chapter 15 Complicated Deliveries:

    Overview, 146

    Chapter 16 Obstetric Analgesia and

    Anesthesia, 159

    P A R T V


    Chapter 17 Impact of the Human Genome

    Project on Neonatal Care, 173

    Chapter 18 Prenatal Genetic Diagnosis, 180

    Diana W. Bianchi

    Chapter 19 Evaluation of the Dysmorphic

    Infant, 186

    Chapter 20 Specific Chromosome Disorders

    in Newborns, 196

    P A R T VI

    Metabolic and Endocrine Disorders

    of the Newborn

    Chapter 21 Introduction to Metabolic and

    Biochemical Genetic Disease, 209


    xviii CONTENTSChapter 22 Inborn Errors of Carbohydrate,

    Ammonia, Amino Acid, and

    Organic Acid Metabolism, 215

    Chapter 23 Lysosomal Storage, Peroxisomal,

    and Glycosylation Disorders

    and Smith-Lemli-Opitz Syndrome

    in the Neonate, 239

    Chapter 24 Skeletal Dysplasias and

    Connective Tissue Disorders, 258

    P A R T VII

    Care of the Healthy Newborn

    Chapter 25 Initial Evaluation: History and

    Physical Examination of the

    Newborn, 277

    Chapter 26 Routine Newborn Care, 300

    Chapter 27 Newborn Screening, 316

    Chapter 28 Resuscitation in the Delivery

    Room, 328

    P A R T VIII

    Care of the High-Risk Infant

    Chapter 29 Stabilization and Transport

    of the High-Risk Infant, 341

    Chapter 30 Temperature Regulation of the

    Premature Neonate, 357

    Chapter 31 Acid-Base, Fluid, and Electrolyte

    Management, 367

    Chapter 32 Care of the Extremely Low-

    Birthweight Infant, 390

    Chapter 33 Care of the Late Preterm

    Infant, 405

    Chapter 34 Pharmacokinetics,


    and Pharmacogenetics, 417

    Chapter 35 Neonatal Pain and Stress:

    Assessment and Management, 429

    P A R T IX

    Immunology and Infections

    Chapter 36 Immunology of the Fetus

    and Newborn, 445

    Chapter 37 Viral Infections of the Fetus and

    Newborn and Human Immunodeficiency Virus

    Infection During Pregnancy, 468

    Chapter 38 Toxoplasmosis, Syphilis, Malaria,

    and Tuberculosis, 513

    Chapter 39 Neonatal Bacterial Sepsis, 538

    Chapter 40 Health Care - Acquired Infections

    in the Nursery, 551

    Chapter 41 Fungal Infections in the

    Neonatal Intensive Care Unit, 565

    P A R T X

    Respiratory System

    Chapter 42 Lung Development: Embryology,

    Growth, Maturation,

    and Developmental Biology, 571

    Maria Victoria Fraga * Susan Guttentag

    Chapter 43 Control of Breathing, 584

    Estelle B. Gauda * Richard J. Martin

    Chapter 44 Pulmonary Physiology

    of the Newborn, 598

    Chapter 45 Principles of Respiratory

    Monitoring and Therapy, 612

    Chapter 46 Respiratory Distress

    in the Preterm Infant, 633

    Chapter 47 Respiratory Failure in the Term

    Newborn, 647

    Chapter 48 Bronchopulmonary Dysplasia, 658

    Chapter 49 Surgical Disorders of the Chest

    and Airways, 672CONTENTS xix

    P A R T XI

    Cardiovascular System

    Chapter 50 Embryology and Physiology

    of the Cardiovascular System, 699

    Chapter 51 Cardiovascular Compromise

    in the Newborn Infant, 714

    Chapter 52 Persistent Pulmonary

    Hypertension, 732

    Chapter 53 Fetal and Neonatal

    Echocardiography, 741

    Chapter 54 Patent Ductus Arteriosus

    in the Preterm Infant, 751

    Chapter 55 Congenital Heart Disease, 762

    Chapter 56 Arrhythmias in the Fetus

    and Newborn, 789

    Chapter 57 Neurodevelopmental Outcomes

    in Children with Congenital

    Heart Disease, 801

    P A R T XII

    Neurologic System

    Chapter 58 Developmental Physiology of

    the Central Nervous

    System, 811

    Chapter 59 Neonatal Neuroimaging, 816

    Chapter 60 Congenital Malformations

    of the Central Nervous

    System, 844

    Chapter 61 Central Nervous System Injury

    and Neuroprotection, 869

    Chapter 62 Neonatal Neuromuscular

    Disorders, 892

    Chapter 63 Neonatal Seizures, 901

    Chapter 64 Risk Assessment and


    Outcomes, 920

    P A R T XIII


    Chapter 65 Breastfeeding, 937

    Chapter 66 Enteral Nutrition for the

    High-Risk Neonate, 952

    Chapter 67 Parenteral Nutrition, 963

    P A R T XIV

    Gastrointestinal System

    Chapter 68 Developmental Anatomy

    and Physiology of the

    Gastrointestinal Tract, 973

    Chapter 69 Structural Anomalies of the

    Gastrointestinal Tract, 979

    Chapter 70 Innate and Mucosal Immunity in

    the Developing Gastrointestinal

    Tract: Relationship to Early and

    Later Disease, 994

    Chapter 71 Abdominal Wall Problems, 1007

    Chapter 72 The Developing Intestinal

    Microbiome: Implications

    for the Neonate, 1016

    Chapter 73 Necrotizing Enterocolitis

    and Short Bowel Syndrome, 1022

    Chapter 74 Disorders of the Liver, 1030

    P A R T XV

    Hematologic System and Disorders

    of Bilirubin Metabolism

    Chapter 75 Developmental Biology of the

    Hematologic System, 1047

    Chapter 76 Hemostatic Disorders of the

    Newborn, 1056

    Chapter 77 Erythrocyte Disorders in

    Infancy, 1080CONTENTSChapter 78 Neonatal Leukocyte Physiology

    and Disorders, 1108

    Chapter 79 Neonatal Indirect

    Hyperbilirubinemia and

    Kernicterus, 1123

    P A R T XVI


    Chapter 80 Congenital Malignant

    Disorders, 1143

    P A R T XVII

    Renal and Genitourinary Systems

    Chapter 81 Renal Morphogenesis and

    Development of Renal

    Function, 1165

    Chapter 82 Clinical Evaluation of Renal and

    Urinary Tract Disease, 1176

    Chapter 83 Developmental Abnormalities of

    the Kidneys, 1182

    Chapter 84 Developmental Abnormalities of

    the Genitourinary System, 1191

    Chapter 85 Acute Kidney Injury and Chronic

    Kidney Disease, 1205

    Chapter 86 Glomerulonephropathies

    and Disorders of Tubular

    Function, 1222

    Chapter 87 Urinary Tract Infections and

    Vesicoureteral Reflux, 1228

    Chapter 88 Renal Vascular Disease in the

    Newborn, 1235


    Endocrine Disorders

    Chapter 89 Embryology, Developmental

    Biology, and Anatomy of the

    Endocrine System, 1245

    Chapter 90 Disorders of Calcium and

    Phosphorus Metabolism, 1255

    Chapter 91 Disorders of the Adrenal

    Gland, 1274

    Chapter 92 Ambiguous Genitalia in the

    Newborn, 1286

    Chapter 93 Disorders of the Thyroid

    Gland, 1307

    Chapter 94 Disorders of Carbohydrate

    Metabolism, 1320

    P A R T XIX

    Craniofacial and Orthopedic


    Chapter 95 Craniofacial

    Malformations, 1331

    Chapter 96 Common Neonatal Orthopedic

    Ailments, 1351

    P A R T XX

    Dermatologic Conditions

    Chapter 97 Newborn Skin: Development

    and Basic Concepts, 1363

    Chapter 98 Congenital and Hereditary

    Disorders of the Skin, 1373

    Chapter 99 Infections of the Skin, 1390

    Chapter 100 Common Newborn

    Dermatoses, 1397

    Chapter 101 Cutaneous Congenital

    Defects, 1406

    P A R T XXI

    The Eye

    Chapter 102 Disorders of the Eye, 1423


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