Autoimmune Disease Models

Edited by

  • Irun Cohen, The Weizman Institute of Science, Rehovot, Israel
  • Ariel Miller, The Weizman Institute of Science, Rehovot, Israel

Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
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Book information

  • Published: November 1994
  • Imprint: ACADEMIC PRESS
  • ISBN: 978-0-12-178330-3


Table of Contents

S. Brocke, K. Gijebels, And L. Steinman, Experimental Autoimmune Encephalomyelitis in the Mouse. A. Alsabbagh and H.L. Weiner, Rat Experimental Autoimmune Encephalomyelitis. S.D. Miller, W.J. Karpus, J.G. Pope, M.C. Dal Canto, And R.W. Melvold, Theiler's Virus-Induced Demyelinating Disease. C. Linington and H. Wekerle, Experimental Allergic Neuritis. R.R. Caspi, Experimental Autoimmune Uveoretinitis (Eau), A. Vincent, Experimental Autoimmune Myasthenia Gravis. G. Wick, R. Cole, H. Dietrich, Ch. Maczek, P.-U. Muller, And K. Hala, The Obese Strain (Os) With Spontaneous Autoimmune Thyroiditis as a Model for Hashimoto Disease. Y.-C.M. Kong and A.A. Giraldo, Experimental Autoimmune Thyroiditis in the Mouse and Rat. D. Elias, The Nod Mouse. P.A. Gottlieb and A.A. Rossini, The Bb Rat Models of Iddm. N.R. Rose and D.A. Neumann, Experimental Myocarditis. A.W. Lohse and K.-H. Meyer Zum Buschenfelde, Experimental Hepatitis. M.H.M. Wauben, J.P.A. Wagenaar-Hilbers, And W. Van Eden, Adjuvant Arthritis. C. Putterman and Y. Naparstek, Murine Models of Spontaneous Systematic Lupus Erythematosus. M.N. Hart and Z. Fabry, Autoimmune Vasculitis. K.S.K. Tung, O. Taguchi, And C. Teuscher, Testicular and Ovarian Autoimmune Diseases. S. Florquin and M . Goldman, Allogenic Diseases. H. Van Herck, V. Baumans, And S.F. De Boer, Assessment of Discomfort in Laboratory Animals.