Atlas of Orthopedic Pathology

with CD-ROM


  • Lester Wold, MD, Professor and Chairman, Department of Pathology, Mayo Clinic, Rochester, MN
  • K. Krishnan Unni, MD, Professor and Director, Orthopedic Pathology, Department of Pathology, Mayo Clinic, Rochester, MN
  • Franklin Sim, MD, Consultant, Department of Orthopedic Surgery, Chair, Division of Orthopedic Oncology, Mayo Clinic, Rochester, MN
  • Murali Sundaram, MD, Consultant Radiologist, Department of Diagnostic Radiology, Cleveland Clinic Foundation, Cleveland, OH

This authoritative resource illustrates and discusses the pathologic, radiographic, and differential diagnostic aspects and clinicopathological correlations for a full range of neoplastic and non-neoplastic conditions of the bones and joints. A bulleted, outline format makes reference quick and easy, and a bonus CD-ROM—new to this edition—offers all of the book’s illustrations in electronic format.
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Book information

  • Published: April 2008
  • Imprint: SAUNDERS
  • ISBN: 978-1-4160-5328-6


"To turn the pages of this largely pictorial tome, is to wonder at the brilliance of the photomicrographic reproduction (many reminiscent of the designs on William Morris wallpaper), the clarity of the radiographs and the breadth of permutations of tumour-like disease. It is clear the that the work comes from a Centre of Excellence."
Journal of Bone and Joint Surgery, August 2009

"An exceptionally well presented concise guide. The book consists of wide range of clinical, radiological and pathologic descriptions accompanied by radiographs, photographs of gross appearances and histological pictures of various orthopaedic pathological conditions", March 2013

Table of Contents


1. Hyperparathyroidism

2. Osteoporosis

3. Renal Osteodystrophy

4. Rickets

5. Osteomalacia

6. Oncogenic Osteomalacia (Phosphaturic Mesenchymal Tumor)

7. Paget’s Disease

8. Camurati-Engelmann Disease (Progressive Diaphyseal Dysplasia)

9. Hypertrophic Osteoarthropathy

10. Melorheostosis

11. Osteopetrosis

12. Osteogenesis Imperfecta

13. Fluorosis

14. Gaucher’s Disease

15. Osteoarthritis

16. Neuropathic Joint (Charcot's Joint)

17. Rheumatoid Arthritis

18. Ochronosis—Disorder of Tyrosine and Phenylalanine Catabolism Secondary to Homogentisic Acid and Related Compounds

19. Gout

20. Chondrocalcinosis (Pseudogout, Calcium Pyrophosphate Dihydrate Crystal Deposition Disease)

21. Amyloidosis

22. Xanthomatosis

23. Fibrous Dysplasia

24. Osteofibrous Dysplasia

25. Ankylosing Spondylitis

26. Synovial Chondromatosis

27. Pigmented Villonodular Synovitis

28. Arthroplasty Effect


Section 2A: Bone-Forming Tumors

29. Osteoid Osteoma

30. Osteoblastoma

31. Osteosarcoma (Conventional)

32. Parosteal Osteosarcoma

33. Periosteal Osteosarcoma

34. High-Grade Surface Osteosarcoma

35. Telangiectatic Osteosarcoma

36. Low-Grade Central Osteosarcoma

37. Small Cell Osteosarcoma

Section 2B: Cartilage-Forming Tumors

38. Osteochondroma

39. Chondroma

40. Chondroblastoma

41. Chondromyxoid Fibroma

42. Multiple Chondromas

43. Periosteal Chondroma

44. Chondrosarcoma

45. Chondrosarcoma Arising in Osteochondroma

46. Dedifferentiated Chondrosarcoma

47. Mesenchymal Chondrosarcoma

48. Clear Cell Chondrosarcoma

Section 2C: Fibrous and Fibrohistiocytic Tumors

49. Benign Fibrous Histiocytoma

50. Fibrosarcoma

51. Malignant Fibrous Histiocytoma

Section 2D: Hematopoietic Tumors

52. Malignant Lymphoma

53. Myeloma

54. Mastocytosis (Mast Cell Disease)

55. Langerhans’ Cell Histiocytosis (Histiocytosis X)

Section 2E: Vascular Tumors

56. Hemangioma

57. Hemangioendothelioma, Epithelioid Hemangioendothelioma, and Angiosarcoma

Section 2F: Tumors of Unknown Origin

58. Hemangiopericytoma

59. Giant Cell Tumor

60. Malignancy in Giant Cell Tumor (Malignant Giant Cell Tumor)

61. Adamantinoma

62. Chordoma

63. Ewing’s Sarcoma

Section 2G: Secondary Sarcomas

64. Paget’s Sarcoma

65. Postradiation Sarcoma

Section 2H: Tumor-Like Conditions

66. Neurilemmoma

67. Aneurysmal Bone Cyst

68. Unicameral Bone Cyst (Simple Cyst)

69. Giant Cell Reaction (Giant Cell Reparative Granuloma)

70. Fibroma (Metaphyseal Fibrous Defect)

71. Avulsive Cortical Irregularity (Fibrous Cortical Defect, Periosteal Desmoid)

72. Mesenchymal Hamartoma of the Chest Wall

73. Osteomyelitis

74. Avascular Necrosis

75. Massive Osteolysis (Gorham’s Disease)

76. Hemophilia

77. Metastatic Carcinoma

78. Sarcoidosis

79. Bizarre Parosteal Osteochondromatous Proliferation (BPOP)

80. Erdheim-Chester Disease