Atlas of Ocular Blood Flow

Vascular Anatomy, Pathophysiology, and Metabolism


  • Alon Harris, MSc, PhD, Professor of Ophthalmology, Professor of Physiology and Biophysics; Letzer Endowed Chair at the Indiana University School of Medicine, Indianapolis, IN

In the second edition of Atlas of Ocular Blood Flow, Dr. Alon Harris details the vascular anatomy and physiology of the eye, analyzes the eye’s blood supply, and evaluates the latest technologies available for assessing patients. He shows you how irregular ocular blood flow patterns can indicate systemic or medication-related conditions, and presents images and actual case reports to illustrate the use of new technologies such as OCT with Doppler application and non-invasive retinal oximetry. With more than 400 illustrations, most in full color, this is the only atlas worldwide that gives you pictorial presentations, anatomical illustrations, and detailed descriptions of the methods available to measure blood flow.
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Ophthalmology practitioners, residents and Optometrists.


Book information

  • Published: March 2010
  • ISBN: 978-1-4377-1737-2


This is an informative and richly illustrated atlas that contains practical and useful information about normal and abnormal ocular blood flow and its assessment. This book will appeal to clinicians and scientists with an interest in ocular blood flow. Also, the atlas will provide essential information for trainees with a special interest in the field.
--Graefe's Arch Clin Exp Ophthalmology, 242:687, 25 June 2004

Table of Contents

I. Ocular vasculature, anatomical structure and function
1. Anatomy (different illustrations on anatomical structures in the orbit)

a. Description of vasculature (and anatomic variations) beginning from the heart to the ophthalmic vein
b. Innervation

2. Vascular physiology: Controls in general terms
a. Innervation
b. Autoregulation (e.g., intracular pressure)
c. Relationship between blood pressure and blood flow in these vessels
d. Intraocular pressure and blood flow to these vessels
e. Different influencing factors (e.g. mediators of vessel dilation, vasoconstrictors) with diagrams showing affection of vessels

3. Pathophysiology
a. Loss of innervation (Horner syndrome
b. Ion channel dysfunction (theory)
c. Vasospasm (clinical observation, cold hand, migraine, raynaud)
d. Gas perturbations (hyperoxia, hypoxia, hypercapnia) and pharmacology

II. Principles of technology (including diagrams)
4. Ultrasound

a. Physical basics and anatomical description with illustrations
b. History/early measurements
c. Contemporary measurements
d. Clinical examples

5. Angiography
a. Physical basics and anatomical description
b. History/early measurements
c. Contemporary measurements
d. Clinical

6. Laser Doppler technologies
a. Physical basics and amatomical description
b. History/early measurements
c. Comtemporary measurements
d. Clinical examples

7. Pulsatility based techniques
a. Physical basics and anatomical description
b. History/early measurements
c. Contemporary measurements
d. Clinical examples

III. Principal applicability to diseases (examples of altered circulation)
8. Glaucoma (visual acuity, contrast sensitivity, visual fields, blood flow)

b. NTG
d. Other; one image per subdivision

9. Age-related macular degeneration
a. One photo per stage, beginning with pigment shift, ending with subretinal meovascularization

10. Diabetic retinopathy

11. Arteriitic and non-arteriitic ischemic neuropathy

12. Vascular occlusions

a. Arterial occulusion
b. Vein occlusion
c. Partial vessel occlusion (one-vessel-branch)
d. Remaining macular vessel

13. Infections
a. Histoplasmosis
b. CMV
c. Toxoplasmosis
d. Any other infection related to blood flow disorders

14. Degenerative diseases
a. Retinitis pigmentosa
b. Any other disease related to vascular disorders (eg, vaskulitis)

IV. New techniques and their future application