Atlas of Clinical Neurology book cover

Atlas of Clinical Neurology

Atlas of Clinical Neurology, by David Perkin, Douglas C. Miller, Russell Lane, Maneesh C. Patel, and Fred H. Hochberg, delivers the most powerful, clinically oriented image collection of any reference in your specialty - to help you accurately diagnose any condition you see in practice! Approximately 2,000 large, high-quality images - 1,000 in full color - capture the characteristic physical examination and imaging findings of every type of neurological disorder. All of the diagnostic imaging studies have been updated to reflect the dramatic advances in neuroimaging. Updates throughout include a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders. Online access at www.expertconsult.com enables you to reference this masterwork from any computer and download all of the images. The result is the ultimate diagnostic resource in neurology!

Audience

Neurologists, Residents, Neuroradiologists and Neuropathologists.

Hardbound, 464 Pages

Published: October 2010

Imprint: Saunders

ISBN: 978-0-323-03275-9

Contents

  • 1 Neurologic 1Investigation

    The Cerebrospinal Fluid, 1

    Plain Radiography, 1

    Ultrasound: Noninvasive Scanning, 2

    Computed Tomographic Scanning, 2

    Magnetic Resonance Imaging, 2

    Digital Subtraction Angiography, 13

    Interventional Techniques, 13

    Radioisotope Imaging, 15

    Electrophysiology, 16

    Electromyography, 20

    Biopsy, 22

    2 Motor Neuron 28and Peripheral Nerve Diseases

    Pathogenesis of Motor Neuron Disease, 28

    Clinical Variants of Classic Motor Neuron Disease, 28

    Atypical Amyotrophic Lateral Sclerosis, 30

    Monomelic Amyotrophy, 31

    Acquired Sporadic Motor Neuron Diseases, 31

    Genetic Motor Neuron Diseases, 31

    Spinal Muscular Atrophies, 31

    Other Forms of Spinal Muscular Atrophy, 33

    Bulbar Syndromes, 33

    Familial Motor Neuron Disease, 33

    Peripheral Nerve Diseases, 33

    Peripheral Neuropathy, 33

    Genetically Determined Neuropathies, 34

    Charcot-Marie-Tooth Disease, 34

    Hereditary Neuropathy with Liability to Pressure Palsies, 36

    Hereditary Sensory and Autonomic Neuropathy, 36

    Hereditary Neuralgic Amyotrophy, 36

    Neuropathies as Part of Genetic Systemic Neurologic Diseases, 37

    Porphyria, 37

    Disorders of Lipid Metabolism, 38

    Familial Amyloid Polyneuropathies, 38

    Metachromatic Leukodystrophy, 38

    Polyneuropathies in Acquired Systemic Diseases, 39

    Diabetic Neuropathy, 39

    Nutritional and Deficiency Disorders, 41

    Paraproteinemic Neuropathies, 41

    Infectious and Postinfectious Causes, 42

    Chronic Inflammatory Demyelinating Polyradiculoneuropathy, 43

    Connective Tissue Disorders, 44

    Toxic Neuropathies, 44

    Paraneoplastic Neuropathies, 44

    Neuropathy of Unknown Cause, 45

    The Mononeuropathies, 45

    3 Myopathies 57and Myasthenia

    Genetic Myopathies, 57

    Muscular Dystrophies and Related Disorders, 57

    Myotonic Dystrophies and Non-dystrophic Myotonias, 65

    Congenital Myopathies, 69

    Mitochondrial Myopathies, 70

    Metabolic Myopathies, 72

    Acquired Myopathies, 74

    Inflammatory Immune-Mediated Myopathies, 74

    Myopathies in Systemic Diseases, 77

    Toxin- and Drug-Induced Myopathies, 79

    Myasthenia Gravis and Other Neuromuscular Transmission Disorders, 81

    4 Cerebrovascular 99Disease: Cerebral Infarction

    Anatomy, 99

    Classification, 99

    Cerebral Infarction, 99

    Pathologic and Physiologic Consequences of Cerebral Infarction, 102

    Investigation, 103

    Clinical Syndromes, 109

    Other Causes of Cerebral Infarction, 116

    Hypertensive Encephalopathy, 121

    Clinical Examination, 121

    5 Cerebral Hemorrhage 143and Other Cerebrovascular Disorders

    Cerebral Hemorrhage, 143

    Clinical Features, 143

    Investigation of Suspected Hematoma, 146

    Nonhypertensive Intracerebral Hemorrhages, 147

    Vascular Malformations, 147

    Cerebral Amyloid Angiopathy, 153

    Coagulation Disorders, 153

    Aneurysms, 154

    Cerebral Venous Thrombosis, 158

     

    6 Dementia Syndromes 169

    Alzheimer’s Disease, 169

    Macroscopic Appearance, 169

    Microscopic Appearance, 169

    Clinical Features, 169

    Investigation, 170

    Treatment, 170

    Dementia and Lewy Bodies, 170

    Frontotemporal Dementia and Lobar Atrophies, 170

    Frontotemporal Lobar Degeneration with Tau Pathology, 172

    Pick’s Disease, 172

    Familial Taupathies, 174

    Frontotemporal Lobar Degeneration with Ubiquitin-Only Immunoreactive Changes, 174

    Arteriosclerotic Dementia, 174

    Imaging, 174

    7 Extrapyramidal 176Disorders

    Parkinson’s Disease, 176

    Clinical Features, 176

    Investigation, 176

    Treatment, 176

    Postencephalitic Parkinsonism, 180

    Atypical Parkinsonian Disorders, 182

    Progressive Supranuclear Palsy, 182

    Frontotemporal Dementia and Parkinsonism, 183

    Corticobasal Degeneration, 184

    Multisystem Atrophy, 185

    Other Parkinsonian Syndromes, 186

    Arteriosclerotic Parkinsonism, 186

    Dystonia, 186

    Primary Dystonia, 186

    Secondary Dystonias, 189

    Choreiform and Ballistic Movements, 191

    Other Choreiform Disorders, 193

    8 Intracranial Tumors: 201Paraneoplastic (Nonmetastatic) Neurologic Syndromes

    Clinical Features of Intracranial Tumors, 201

    The Investigation of Intracranial Tumors, 202

    Treatment of Brain Tumors: General Considerations, 206

    Specific Tumors, 207

    Metastases, 207

    Primary Intraaxial Brain Tumors, 207

    Tumors in or Adjacent to the Ventricular System, 214

    Embryonal CNS Tumors, 216

    Nonneuroepithelial Intraaxial CNS Tumors, 217

    Primary Extraaxial Brain Tumors, 219

    The Nonmetastatic (Paraneoplastic) Cerebral and Cerebellar Syndromes, 224

    9 Spinal Tumors 249and Paraneoplastic Disorders

    Clinical Features of Spinal Tumors, 249

    Investigation of Spinal Tumors, 249

    Specific Tumors, 253

    Intramedullary Tumors, 253

    Tumors of the Spinal Meninges, 255

    Tumors of the Epidural Space and Spine, 256

    10 Developmental 266and Familial Disorders

    Neural Tube Defects, 266

    Spina Bifida Occulta, 266

    Spina Bifida Cystica, 266

    Chiari Malformations, 267

    Dandy-Walker Syndrome, 268

    Lhermitte-Duclos Syndrome, 268

    Agenesis of the Corpus Callosum, 269

    Anomalies of the Septum Pellucidum, 269

    Neuronal Migration Defects, 270

    Disorders of Diverticulation, 271

    Neuronal Heterotopias in Cerebral White Matter, 272

    Arachnoid Cysts, 272

    Porencephaly, 272

    Hydrocephalus, 273

    Normal Pressure Hydrocephalus, 274

    Tuberous Sclerosis (Bourneville’s Disease), 275

    Neurofibromatosis (Von Recklinghausen’s Disease), 276

    Familial Disorders Affecting the Cerebellum, 278

    11 Pain Syndromes 289and Trauma

    Headache, 289

    Primary Headaches, 289

    Secondary Headaches, 295

    Neuralgias, 298

    Cranial Neuralgias, 298

    Postherpetic Neuralgia, 300

    Causalgia and Reflex Sympathetic Dystrophy, 300

    Head Injury, 300

    Severity of Head Injury, 300

    Mechanisms of Brain Injury, 301

    Chronic Complications of Head Injury, 304

    Spinal Injury, 305

    Injury to Both Bony and Neurologic Structures, 305

    Spinal Cord Syndromes, 310

    12 Infections 312

    The Meningitides, 312

    Viral Meningitis, 312

    Bacterial Meningitis, 312

    Tuberculous Meningitis, 313

    Cryptococcal Meningitis, 314

    Parenchymal Infections: Cerebritis, Encephalitis, Abscess, Subdural Empyema, 314

    Fungal Encephalitis, 314

    Parasitic Infection, 316

     

    Spinal Cord Infarction, 376

    Spinal Extradural Hematoma, 377

    Amyloidosis, 378

    Anterior Herniation of the Cord, 378

    15 Cranial Neuropathies 386

    The First Cranial Nerve (Olfactory), 386

    The Second Cranial Nerve (Optic), 386

    Orbital Tumors, 386

    Pupillary Syndromes, 387

    The Third Cranial Nerve (Oculomotor), 389

    The Fourth Cranial Nerve (Trochlear), 391

    The Sixth Cranial Nerve (Abducens), 391

    Orbital Lesions, 391

    Brainstem Oculomotor Syndromes, 396

    Other Horizontal Gaze Disorders, 401

    The Fifth Cranial Nerve (Trigeminal), 401

    The Seventh Cranial Nerve (Facial), 402

    The Eighth Cranial Nerve (Acoustic), 405

    The Ninth, Tenth, Eleventh, and Twelfth Cranial Nerves, 408

    Combined Cranial Nerve Palsies, 408

    16 Neurologic Aspects 413Of Systemic Disease

    Radiation Damage, 413

    Radiation Damage to Extracranial Vessels, 413

    Alcohol and the Nervous System, 413

    Central Pontine Myelinolysis, 417

    Marchiafava-Bignami Disease, 418

    The Neurology of Endocrine Disease, 418

    Pituitary Disorders, 418

    Adrenal Disorders, 418

    Thyroid Disorders, 418

    Parathyroid Disorders and Abnormalities of Calcium Metabolism, 418

    Paget’s Disease, 418

    Pancreatic Disease, 418

    Neurologic Features of Vasculitis, 420

    Systemic Necrotizing Vasculitis, 420

    Hypersensitivity Vasculitides, 421

    Systemic Granulomatous Vasculitides, 421

    Connective Tissue Disorders, 422

    Systemic Lupus Erythematosus, 422

    Scleroderma, 422

    Sjögren’s Syndrome, 423

    Behçet’s Disease, 423

    Vasculitis Associated with Infection, 423

    Sarcoidosis, 423

    Conversion Syndromes, 424

    17 Epilepsy 434

    Partial Seizures, 434

    Generalized Seizures, 434

    Causes of Epilepsy, 434

    Investigation, 435

    Magnetic Resonance Imaging, 436

    Single-Photon Emission Computed Tomography, 439

    Positron Emission Tomography, 439

    Therapy, 440

    Adverse Drug Effects, 441

    Index, 449

    Bacterial Cerebritis, 318

    Cerebral Bacterial Abscess, 319

    Subdural Empyema, 321

    Encephalitis, 322

    Viral Encephalitis, 322

    Acquired Immune Deficiency Syndrome, 328

    Peripheral Nerve Complications, 329

    Opportunistic Viral Encephalitides in AIDS, 329

    Nonviral Opportunistic Infections in AIDS, 330

    Cerebral Lymphoma in AIDS, 332

    CNS Diseases Caused by Spirochetes, 332

    Syphilis, 332

    Lyme Disease, 334

    Leptospirosis, 334

    Prion Disease, 335

    Creutzfeldt-Jakob Disease, 335

    Variant Creutzfeldt-Jakob Disease, 336

    13 Multiple Sclerosis 343and Other Demyelinating Disorders

    Multiple Sclerosis, 343

    Pathology, 343

    Pathophysiology, 345

    Clinical Features, 346

    Investigation, 347

    Devic’s Disease (Neuromyelitis Optica), 349

    Baló’s Disease, 349

    Schilder’s Disease, 349

    Acute Disseminated Encephalomyelitis, 350

    The Leukodystrophies, 350

    Lysosomal Disorders, 350

    Peroxisomal Disorders, 352

    Other White Matter Disorders, 352

    14 Spinal Disorders 360

    Degenerative Disease of the Spine, 360

    Cervical Disc Disease, 360

    Investigation, 360

    Management, 362

    Thoracic Disc Disease, 362

    Lumbosacral Disc Disease, 362

    Investigation of Lumbosacral Disc Disease, 363

    Spinal Stenosis, 364

    Paget’s Disease of the Spine, 364

    Rheumatoid Arthritis and the Spine, 365

    Infection, 366

    Spinal Epidural Abscess, 366

    Tuberculous Disease of the Spine, 367

    Brucellosis, 368

    Schistosomiasis, 368

    HTLV-1-Associated Myelopathy, 369

    Arachnoid Cysts, 369

    Arachnoiditis, 369

    Vascular Abnormalities of the Spine and Cord, 370

    Spinal (Pial) Arteriovenous Malformations, 370

    Spinal Dural Arteriovenous Fistulas, 373

    Cavernous Hemangioma (Cavernoma), 373

    Vertebral Body Hemangiomas, 373

    Subacute Combined Degeneration of the Spinal Cord, 374

    Radiation Myelopathy, 375

    Syringomyelia, 375

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