Applications of Advanced Omics Technologies: From Genes to Metabolites book cover

Applications of Advanced Omics Technologies: From Genes to Metabolites

The book contains contributions concerning the application of the new instrumental and methodological developments in omics technologies, including those related to Genomics, Transcriptomics, Proteomics, Peptidomics and Metabolomics, Lipidomics and Foodomics.
The16 chapters discuss in detail: innovative applications of functional gene microarrays for profiling microbial communities, microRNA profiling, novel genotyping applications using microarray technology in cancer research, next-generation sequencing applied to the study of human microbiome, emerging RNA-SEQ applications in food science, recent progress in plant proteomics, applications of gel-free proteomic approaches, the challenges and applications of proteomics tools for food authenticity, the role of salivary peptidomics in clinical applications, metabolomic approaches to the study of degenerative, cardiovascular and renal diseases, and neonatal medicine. Also covered are other omics applications such as profiling of genetically modified organisms, the fundamentals, applications and challenges of foodomics, and MS-based lipidomics. Moreover, this volume includes relevant and updated aspects on bioinformatics, data treatment, data integration and systems biology.
This book complements the previous volume "Fundamentals of Advanced Omics Technologies: New Advances from Genes to Metabolites" that covered the fundamental aspects of these new omics technologies.

Audience

Analytical scientists, PhD students and technicians in control laboratories, universities, hospitals, research laboratories and regulation agencies

Hardbound, 496 Pages

Published: June 2014

Imprint: Elsevier

ISBN: 978-0-444-62650-9

Contents

  • Ch. 1. Applications of Functional Gene Microarrays for Profiling Microbial Communities. Joy D. Van Nostrand and Jizhong Zhou
    Ch. 2. MicroRNA Profiling: An Overview of Current Technologies and Applications. Sinead M. Smith and David W. Murray
    Ch. 3. Application of Novel Genotyping Microarray Technologies in Cancer Research. Ricardo Ramos, Juan Moreno-Rubio, Enrique Casado, Guillermo Reglero and Ana Ramírez de Molina
    Ch. 4. Applications of Next Generation Sequencing Technologies to the Study of the Human Microbiome. Philip Chuang, Emily Walsh, Timothy Yen and Ilseung Cho
    Ch. 5. Emerging RNA-Seq Applications in Food Science. Alberto Valdés, Carolina Simó, Clara Ibáñez and Virginia García-Cañas
    Proteomics and Peptidomics
    Ch. 6. Making Progress in Plant Proteomics for Improved Food Safety. Pier Giorgio Righetti, Elisa Fasoli, Alfonsina D’Amato and Egisto Boschetti
    Ch. 7. Advantages and Applications of Gel-Free Proteomic Approaches in the Study of Prokaryotes. John P. Bowman
    Ch. 8. Proteomics Tools for Food Fingerprints. Addressing New Food Quality and Authenticity Challenges. Mónica Carrera, Benito Cañas and José M. Gallardo
    Ch. 9. Salivary Peptidomics Targeting Clinical Applications. Rui Vitorino, Rita Ferreira, Armando Caseiro and Francisco Amado
    Metabolomics
    Ch. 10. Metabolomics in the Study of Alzheimer's Disease. Clara Ibáñez, Alberto Valdés, Virginia García-Cañas and Carolina Simó
    Ch. 11. Application of Metabolomics to Cardiovascular and Renal Disease Biomarker Discovery. Gloria Alvarez-Llamas, Maria G. Barderas, Maria Posada-Ayala, Marta Martin-Lorenzo and Fernando Vivanco
    Ch. 12. The Clinical Application of Proteomics and Metabolomics in Neonatal Medicine. Alan R. Spitzer and Donald H. Chace
    Other Omics Strategies, Data Treatment, Integration and Systems Biology
    Ch. 13. Profiling of Genetically Modified Organisms using Omics Technologies. Alberto Valdés, C. Simó, C. Ibáñez and Virginia García-Cañas
    Ch. 14. MS-Based Lipidomics. Päivi Pöhö, Matej Oresic and Tuulia Hyötyläinen
    Ch. 15. Foodomics. Food Science and Nutrition in the Post-Genomic Era. E. Ibáñez and A. Cifuentes
    Ch. 16. Omics-Data Integration in Systems Biology: Methods and Applications. Ana Conesa and Rafael Hernández

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