Animal Biotechnology

Models in Discovery and Translation

Animal Biotechnology introduces applications of animal biotechnology and implications for human health and welfare. It begins with an introduction to animal cell cultures and genome sequencing analysis and provides readers with a review of available cell and molecular tools. Topics here include the use of transgenic animal models, tissue engineering, nanobiotechnology, and proteomics. The book then delivers in-depth examples of applications in human health and prospects for the future, including cytogenetics and molecular genetics, xenografts, and treatment of HIV and cancers. All this is complemented by a discussion of the ethical and safety considerations in the field.

Animal biotechnology is a broad field encompassing the polarities of fundamental and applied research, including molecular modeling, gene manipulation, development of diagnostics and vaccines, and manipulation of tissue. Given the tools that are currently available and the translational potential for these studies, animal biotechnology has become one of the most essential subjects for those studying life sciences.

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students of biotechnology, biochemistry, molecular medicine, genetics, genomics and other life science courses; researchers in these areas


Book information

  • Published: December 2013
  • ISBN: 978-0-12-416002-6

Table of Contents

Section I: Human Diseases: In Vivo and In Vitro Models
1. Drosophilia: A Model for Biotechnologists
2. Animal Models of Tuberculosis
3. Animal Models for Neurodegenerative Disorders
4. Epigenetics and Animal Models: Applications in Cancer Control and Treatment
5. Development of Mouse Models for Cancer Research
6. Human Papillomavirus (HPV): Diagnosis and Treatment
7. Human DNA Tumor Viruses and Oncogenesis
8. Animal Models for Human Disease
9. HIV Antiretroviral Drugs
10. Animal Biotechnology as a Tool to Understand and Fight Aging

Section II: Animal Biotechnology: Tools and Techniques
11. MultiCellular Spheroid: 3-D Tissue Culture Model for Cancer Research
12. Animal Tissue Culture: Principles and Applications
13. Concepts in Tissue Engineering
14. Nanotechnology and Its Applications to Animal Biotechnology
15. Antibodies: Monoclonal and Polyclonal
16. Molecular Markers: Tool for Genetic Analysis
17. Gene Expression: Analysis and Quantitation
18. Ribotyping: A Tool for Molecular Taxonomy
19. Next Generation Sequencing and Its Applications
20. Biomolecular Display Technology: A New Tool for Drug Discovery
21. In Silico Models: From Simple Networks to Complex Diseases

Section III: Animal Biotechnology: Applications and Concerns
22. Transgenic Animals and their Applications
23. Stem Cells: A Trek from Laboratory to Clinic to Industry
24. Role of Cytogenetics and Molecular Genetics in Human Health and Medicine
25. Antibodies and their Applications
26. Vaccines: Present Status and Applications
27. Safety Assessment of Food Derived from Genetically Modified Crops
28. Nanotechnology and Detection of Microbial Pathogens
29. Biotechnological Exploitation of Marine Animals
30. Herbal Medicine and Biotechnology for the Benefit of Human Health
31. Perspectives on the Human Genome
32. Ethical Issues in Animal Biotechnology