Anesthesia and Analgesia in Laboratory Animals

Edited by

  • Richard Fish, NC State University, College of Veterinary Medicine, Raleigh, USA
  • Peggy Danneman, The Jackson Laboratory, Bar Harbor, ME, USA
  • Marilyn Brown, Charles River Laboratories, East Thetford, VT, USA
  • Alicia Karas, Tufts School of Veterinary Medicine, Department of Clinical Sciences, Anesthesia, North Grafton, MA, USA

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes.
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Veterinary and medical students, senior graduate, graduate students, post-docs, and researchers who utilize animals in biomedical research.


Book information

  • Published: June 2008
  • ISBN: 978-0-12-373898-1


Review of First Edition: "All the contributors should be congratulated on filling an important gap in knowledge, and moreover, filling it to a high standard." --Laboratory Animals

Table of Contents

SECTION I – ANATOMY, PHYSIOLOGY, AND PHARMACOLOGYChapter 1Anatomy, Physiology, and Effects of Pain George J. DeMarco and Peter J. PascoeChapter 2Pharmacology of Injectable Anesthetics, Sedatives, and TranquilizersRobert E. Meyer and Richard E. FishChapter 3Pharmacology of Inhalation AnestheticsDavid B. BrunsonChapter 4Pharmacology of AnalgesicsJames E. Heavner and Dale M. CooperSECTION II – MONITORING AND EQUIPMENTChapter 5Anesthesia Delivery SystemsGeorge A. VoglerChapter 6Monitoring of AnesthesiaJennifer C. Smith and Peggy J. DannemanChapter 7Waste Anesthetic Gas SafetyJennifer C. SmithChapter 8Strategies for Assessing and Minimizing PainAlicia Z. Karas, Peggy J. Danneman, and Joan CadillacChapter 9Post-procedural Care of Commonly Utilized Research Animal SubjectsVictoria A. Hampshire and Judith A. DavisSECTION III – PRACTICAL ANESTHESIA AND ANALGESIA OF TRADITIONAL LABORATORY ANIMAL SPECIESChapter 10Anesthesia and Analgesia in RodentsDiane Gaertner et al. [Diane J. Gaertner, Margaret Batchelder, F. Claire Hankenson and Troy M. Hallman]Chapter 11Anesthesia and Analgesia in RabbitsNeil S. Lipman, Robert P. Marini, and Paula A. FlecknellChapter 12Anesthesia and Analgesia in Nonhuman Primates Sulli J. Popilskis, Donald R. Lee and David B. ElmoreChapter 13Anesthesia and Analgesia in Dogs and CatsElizabeth Armitage-ChanChapter 14Anesthesia and Analgesia of RuminantsAlexander Valverde and Thomas J. DohertyChapter 15Anesthesia and Analgesia in SwineAlison C. Smith and M. Michael SwindleSECTION IV – PRACTICAL ANESTHESIA AND ANALGESIA OF NON-TRADITIONAL LABORATORY ANIMAL SPECIESChapter 16Anesthesia and Analgesia in FerretsJeff Ko and Robert P. MariniChapter 17Anesthesia and Analgesia in Other MammalsJeff Wyatt Chapter 18Anesthesia and Analgesia in BirdsJohn W. LuddersChapter 19Anesthesia and Analgesia in ReptilesDorcas P. O’Rourke and Audrey L. JenkinsChapter 20Anesthesia and Analgesia in AmphibiansDorcas P. O’Rourke and Audrey L. Jenkins Chapter 21Anesthesia and Restraint of Laboratory FishesMichael Stoskopf and Lysa Pam PosnerChapter 22Anesthesia and Analgesia of Invertebrates Cornelia Gunkel and Gregory A. LewbartSECTION V – SPECIAL TOPICS IN ANESTHESIA AND ANALGESIA OF LABORATORY ANIMALSChapter 23Pain Testing in the Laboratory MouseDale J. Langford and Jeffrey S. MogilChapter 24Ethical Issues in Anesthesia and Analgesia in Laboratory AnimalsLarry Carbone and Nelson GarnettChapter 25Regulatory IssuesLynn C. Anderson and Laura ConourChapter 26Management of Chronic PainGeorge DeMarcoChapter 27Anesthesia and Analgesia in the Fetus and NeonateJoanna C. Murrell, David J. Mellor and Craig Johnson Chapter 28Novel Delivery Systems for Analgesic Drugs in Laboratory AnimalsLisa Krugner-Higby, Lesley J. Smith, and Timothy D. HeathChapter 29Non Pharmacologic Pain Control Sara SavageChapter 30Anesthetic Considerations for In Vivo Imaging StudiesAnthony Nicholson and Brenda KlaunbergIndex