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Adverse Effects of Engineered Nanomaterials

Exposure, Toxicology, and Impact on Human Health

Edited by
  • Bengt Fadeel, Karolinska Institutet, Stockholm, Sweden
  • Antonio Pietroiusti, Tor Vergata University, Rome, Italy
  • Anna Shvedova, NIOSH, Morgantown, WV, USA

Adverse Effects of Engineered Nanoparticles: A Disease-Oriented Approach provides a systematic evaluation of representative engineered nanomaterial (ENM) of high volume production and of high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies and the general public need to know about nanosafety.  This book, written by leading international experts in nanotoxicology and nanmoedicine, gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers and patients.  The beneficial applications, both diagnostic and therapeutic, of ENM are also highlighted.  This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, and the clinical and pathological consequences of such exposure in the human population.

Audience
This book is intended for those directly involved in the field of nanosafety, namely professionals in toxicology, pharmacology, occupational medicine, clinical medicine and nanomedicine.

Secondary markets may include workers concerned with safety in the pharmaceutics, cosmetics and public health industries, as well as policy makers developing regulatory frameworks and nanotechnology industries/enterprises.

Hardbound, 360 Pages

Published: January 2012

Imprint: Academic Press

ISBN: 978-0-12-386940-1

Contents

  • Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health
    Edited by Bengt Fadeel, Antonio Pietroiusti & Anna A. Shvedova

    About the Editors
    List of Contributors
    Preface - Bengt Fadeel, Antonio Pietroiusti, Anna A. Shvedova

    ENGINEERED NANOMATERIALS: HAZARD, EXPOSURE, AND SAFETY ASSESSMENT

    1. Interactions with the Human Body - Renato Colognato, Margriet V.D.Z. Park, Peter Wick, Wim H. De Jong
    2. Exposure Assessment - Antonio Bergamaschi, Ivo Iavicoli, Kai Savolainen
    3. Biomonitoring - Enrico Bergamaschi, Andrea Magrini
    4. Critical Evaluation of Toxicity Tests - Maria Dusinska, Elise Rundén-Pran, Sara Correia Carreira, Margaret Saunders
    5. Computational Approaches - Vidana Epa, Dave Winkler, Lang Tran
    6. Regulation and Legislation - Maureen R. Gwinn, Birgit Sokull-Klüttgen,

      7. ENGINEERED NANOMATERIALS: IMPACT ON HUMAN HEALTH

    7. Respiratory System - Ken Donaldson, Craig Poland
    8. Cardiovascular System - Jennifer B. Raftis , Nicholas L. Mills, Rodger Duffin
    9. Neurological System - Sandra Ceccatelli, Giuseppe Bardi
    10. Immune System - Diana Boraschi, Albert Duschl
    11. Skin - Nancy A. Monteiro-Riviere, Francesca Larese Filon
    12. Gastrointestinal Tract - Mark A. Jepson
    13. Reproductive Toxicity - Karin Sørig Hougaard, Luisa Campagnolo
    14. Genotoxicity and Cancer - Shareen H. Doak, Ying Liu, Chunying Chen

      15. BIOMEDICAL APPLICATIONS OF ENGINEERED NANOMATERIALS

    15. Diagnostic Applications - Kai Cheng, Zhen Cheng
    16. Therapeutic Applications of Engineered Nanomaterials- Cyrill Bussy, Christoph Alexiou, Robby A. Petros, Andreas Nyström, Laura Methven, Kostas Kostarelos


    ANNEX:  Synthesis of Nanomaterials - Muhammet S. Toprak, Gulaim A. Seisenbaeva, Vadim G. Kessler
    GLOSSARY
    Index

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