Advances in Antiviral Drug Design
Edited by- E. De Clercq, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium
Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.
Audience
Researchers, academics and postgraduates working in medical virology and infectious diseases, chemotherapy and drug discovery
Included in series
Advances in Antiviral Drug Design
Advances in Antiviral Drug Design
Hardbound, 264 Pages
Published: July 2007
Imprint: Elsevier
ISBN: 978-0-444-52173-6
Contents
- Status presens of antiviral drugs and strategies, Part I: DNA viruses and retrovirusesStatus presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses)Methylenecyclopropane analogues of nucleosides as anti-herpes agentsSynthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonatesCCR5 antagonists for the treatment of HIV infection and AIDSThe medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)
