Acute Toxicology Testing


  • Shayne Gad, Gad Consulting Services, Raleigh, North Carolina, U.S.A.
  • Christopher Chengelis, WIL Research Laboratories, Ashland, Ohio, U.S.A.


Book information

  • Published: October 1997
  • ISBN: 978-0-12-272250-9

Table of Contents

Introduction. Acute Toxicology Program: Study Design and Development. Tests for Dermal Irritation and Corrosion. Ocular Irritation Testing. Dermal Sensitization. Photosensitization/Phototoxicity. Lethality Testing. Safety Considerations for the Administration of Agents By the Parenteral Routes. Acute Systemic Toxicity Tests. Routes, Formulations, And Vehicles. Considerations Specific to Animal Test Models. Statistical Analysis for Acute Toxicology. Acute Inhalation. Problems and Issues. Appendices. Subject Index.