A Pharmacology Primer

Theory, Applications, and Methods

By

  • Terry Kenakin, PhD, Professor of Pharmacology, The University of North Carolina School Of Medicine, Chapel Hill, USA

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.
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Audience

Researchers in all areas of molecular biology who need the background basics of pharmacology. This list includes pharmaceutical companies, drug disocvery professionals, and researchers in pharmacology, biochemistry, cell biology, and molecular biology. Also can be used for upper-level undergrad textbook.

 

Book information

  • Published: October 2006
  • Imprint: ACADEMIC PRESS
  • ISBN: 978-0-12-370599-0


Table of Contents

What is Pharmacology?How Different Tissues Process Drug Response Drug Receptor TheoryPharmacological Assay Formats: Binding Agonists: The Measurement of Affinity and Efficacy in Functional Assays Orthosteric Drug Antagonism Allosteric Drug Antagonism The Process of Drug DiscoveryTarget- and System-based Strategies for Drug Discovery‘Hit’ to Drug: Lead OptimizationStatistics and Experimental DesignSelected Pharmacological MethodsGlossary of Pharmacological TermsAppendices: Statistical Tables Mathematical Fitting Functions