A Historical Perspective on Evidence-Based Immunology
- Edward Moticka, Professor, Department of Immunology and Microbiology, A.T. Still University School of Osteopathic Medicine, Mesa, AZ, U.S.A.
A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights.
The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigenâTCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells.
graduate and undergraduate students entering the fields of immunology, molecular biology and other biomedical disciplines, their instructors and mentors. Researchers, practitioners and those interested in the evolution of ideas and scientific methods will find the text compelling and useful.